Risk Evaluation and Mitigation Strategy (REMS)
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Counseling for All Patients

  • The Medication Guide and patient brochure contain important information that patients should read and become familiar with.
  • Qsymia should be taken in the morning, with or without food.
  • Avoid taking Qsymia in the evening due to the possibility of insomnia.
  • Advise patients to start treatment with Qsymia as follows:
    • Take one Qsymia capsule (containing 3.75 mg of phentermine and 23 mg of topiramate) once each morning for the first 14 days.
    • After the first 14 days is complete, take one Qsymia 7.5 mg/46 mg capsule once each morning
    • Do not take Qsymia 3.75 mg/23 mg and Qsymia 7.5 mg/46 mg capsules together
  • If an increase in Qsymia dose is prescribed after medical evaluation, advise patients to increase the dose of Qsymia as follows:
    • Take one Qsymia 11.25 mg/69 mg capsule once each morning for 14 days
    • After the 14 days is complete, take one Qsymia 15 mg/92 mg capsule once each morning
    • Do not take Qsymia 11.25 mg/69 mg and Qsymia 15 mg/92 mg capsules together
  • Advise patients NOT to stop Qsymia without talking with their HCP as serious side effects such as seizures may occur.

Additional Information and Tools

Additional information and tools can be found at www.QsymiaREMS.com

  • Risk of Birth Defects with Qsymia patient brochure
  • Qsymia Prescribing Information
  • Qsymia Medication Guide

For more information on Qsymia, contact VIVUS Medical Information at 1-888-998-4887 or visit www.Qsymia.com.

For more information the Qsymia REMS, or for information on pharmacy enrollment, contact the Qsymia REMS Phamacy Support Center at 1-855-302-6698 or visit www.QsymiaREMS.com.